Oh, how nice it would be to take a magic pill and not have to diet. Unfortuately, there are always side effects to drugs. Not everyone gets those side effects, but some do. There is a proven way to lose weight: push yourself away from the dining room table after eating small portions of a nutritious meal; don't eat junk foods, and walk after each meal. I know this works. I've lost a total of 166 pounds. 140 of that has been done in the past five years. Hard? Oh, yes. Worth it? Definitely. About these drugs, two contain anti-seizure drugs. Why take something you don't need? If you aren't having seizures, do you need to take a drug that contains a drug to prevent them? If you aren't depressed, do you need to take an anti-depressant? We are a nation of pill poppers. We don't have to be when it comes to losing weight.

I agree with Haggi, you have to take responsiblity for what goes into your body. There is no quick fix or magic pill, you have to eat right, and exercise, plain and simple. The drug companies are going to continue to get rich off of people who want the results but are not willing to work for them.

I was in the lorcaserin study group trial for 12 months. I lost 12% (23 lbs). No side effects. It worked for me by just not wanting to eat as much. I play racquetball three times a week, and my game is now better because I can move to the ball faster. I walk and bike three times a week and that is now also easier. It's been 6 months since the trial was over and I've only gained back 2 lbs. It's been easier to keep the food intake lower.

They don't work as a permanent solution and eventually people build up a tolerance to them. Not sure why anyone would want to take them. We need to focus on less processed foods and eating like people did back in the 50's. Everywhere you turn there is food! Go back to eating three meals a day and a glass of milk with a few cookies for a snack. You didn't see many morbidly obese people 50 + years ago.

We have a few problems here at the cause of obesity. 1.) Lifestyle, we have way to many tech gadgets that make it easy to stay at home on the couch. 2.) Our days are packed full of work, commuting back and forth. 3.) Bringing work home. There are several more out there but they all work hand in hand with each other outside of what we do. Everything we eat these days is out of convience so we can fit it into our schedule. I can almost bet that a lot of people are overweight not because they over eat but because they under eat so their bodies are thinking they are starving. You can also bet that people just aren't active enough. Why grocery shop when you can do it online and have it delivered straight to your house? Why does someone want to go out for a walk when they've just worked 8 hour, and spent 2 hours in the car commuting each way? A pill isn't going to solve weight loss problem if it can't solve all the little problems.

Qnexa sounds like a recipe for disaster. Topiramate, also known as Topomax, when used on people who don't have seizures (which will probably be most of the pill-takers) can really cause severe psychological trauma. Some years ago, a friend of mine was found home, crouching on the floor, crying (an adult male, mind you), after having taken Topomax, which was prescribed to him for weight loss. He said he could not recognize where he was (he was home, the home he had lived in for 5 years), and he said everything looked fake as if he was in a TV set. He weaned himself off and is fine now, eating healthy and taking up exercise instead. Now Qnexa wants to mix that with speed, essentially? Wow. I can see a lot of people needing to see psychiatrists, getting treatment (as in needing pills for various psychological disorders), committing suicide or becoming psychotic, if these pills don't kill their organs first.

I've taken Topamax before, and was lucky enough that I didn't have any of the side effects associated with it, which is mostly memory loss and concentration problems. If people are having other issues then chances are it certainly wasn't the Topamax.

I will be first in line to try it combined with another medication. Due to the way I gained weight (via medical issues), it is EXTREMELY hard for me to take it off, so anything that helps at all is basically a miracle.

For those of you ignorantly spouting that you shouldn't take anti seizure medications if you don't have seizures, please get a grip on reality. Anti-seizure medications are prescribed for a host of other ills, including bipolar disorder, depression, and anxiety. Many, many people are currently taking them for those reasons. For example, I take neurontin, which is an anti convulsant, three times a day to treat my bipolar disorder.