you miss the point as usual. the comentary has nothing to do with funding (obvious if you do not read past the simpicity of those few words) although this had nothing to do with u.s. gov. either. now go back and do a little research into political involvement and stem cells.
This is quite interesting. But they have left out a few significant details. 1. How long does it take to 'nudge' the iPS cells from their embryonic-like stem cell form to adult liver cells? 2. How many transformed iPS cells, cell volume or density, will it take to allow an individual with to recover from severe liver failure? To answer the first question, there needs to be a technology available to culture the iPS cells during which the cells are "reprogrammed" to functioning like adult liver cells by growth factors, cytokines, etc., to generate a significant cell volume that could be used for transplantation or injection.
Using Embryonic stem cells for research is fine, But using an individuals own cells needs to be the ultimate Goal.
Using Embryonic stem cells has one Fatal Flaw if used to produce organs or repair material.
With in a short time your body will reject it. Even taking anti-rejection drugs, rejection is inevitable.
The Researches know this. They only want to use embryonic stem cells for the basic research.
Some of the other research I've read about on stem cells is that they have drastically reduced the time to reprogram the adult stem cells taken from patients.
Also: This must be old Data: I read where liver cells were produced quit some time ago. There are multiple types of Liver cells that have to be produced to produce a liver.
The big hold up on growing a liver is producing a scaffolding structure & getting the proper cells to grow where needed.
One researcher is using donated livers then flushing out all the cells which provides the frame of which has no rejection factors. Still they need to learn how to get the proper cells to grow in the proper places.
I believe I seen this on Tedmed.com. Also shows research being done on Actually Printing a heart with an ink-jet printer in 3D using re-programed stem cells. It may be a possible approach for most organs.
Have a heart problem. Just Hang in there for about 3 weeks while we print you one.
Stem cells do not have HLA markers. They are not recognized as self or non-self by the body, will not be rejected by the body once they are transformed to fully functioning hepatocytes. One problem that does exist, some of the transformed iPS cells may NOT transform. Once delivered to the patient these few untransformed cells could become pre-cancerous cells.
I believe and have believed for a long time that it will be our own skin cells which will emerge as superior to the 'pluripotent' stem cells long heralded as the answer. Murine skin cells from buccal mucosa HAVE ALREADY have already been used to clone living mice. A lot of this work went underground during the Bush era and is only now being published. A real leap ahead in treating malignant organs and systemic organ DZ is not far off. Your own dermatologist might be the go-to medical expert of the the near future when it comes to 'replacement' organs.
It is really interesting and a good step for those people who suffer with the liver diseases. It will helpful because this disease damaged the function of hapetocytes, it may causes hepatocellular necrosis, fibrosis, and regeneration with nodule formation. Turmeric, guduchi and milk thistles are the effective herb treatment. Apart of all this theory of the article is quite interesting.
hey obama did you read this? i guess there is no stopping innovation when government gets out of the way.
hey knowman, guess who funded the study?
you miss the point as usual. the comentary has nothing to do with funding (obvious if you do not read past the simpicity of those few words) although this had nothing to do with u.s. gov. either. now go back and do a little research into political involvement and stem cells.
Would you shut the hell up about Obama already?
This is quite interesting. But they have left out a few significant details. 1. How long does it take to 'nudge' the iPS cells from their embryonic-like stem cell form to adult liver cells? 2. How many transformed iPS cells, cell volume or density, will it take to allow an individual with to recover from severe liver failure? To answer the first question, there needs to be a technology available to culture the iPS cells during which the cells are "reprogrammed" to functioning like adult liver cells by growth factors, cytokines, etc., to generate a significant cell volume that could be used for transplantation or injection.
This is a giant step for humanity...,.lets'see the money trail some progress for mankind.
There but for the grace of God go I!!
Using Embryonic stem cells for research is fine, But using an individuals own cells needs to be the ultimate Goal.
Using Embryonic stem cells has one Fatal Flaw if used to produce organs or repair material.
With in a short time your body will reject it. Even taking anti-rejection drugs, rejection is inevitable.
The Researches know this. They only want to use embryonic stem cells for the basic research.
Some of the other research I've read about on stem cells is that they have drastically reduced the time to reprogram the adult stem cells taken from patients.
Also: This must be old Data: I read where liver cells were produced quit some time ago. There are multiple types of Liver cells that have to be produced to produce a liver.
The big hold up on growing a liver is producing a scaffolding structure & getting the proper cells to grow where needed.
One researcher is using donated livers then flushing out all the cells which provides the frame of which has no rejection factors. Still they need to learn how to get the proper cells to grow in the proper places.
I believe I seen this on Tedmed.com. Also shows research being done on Actually Printing a heart with an ink-jet printer in 3D using re-programed stem cells. It may be a possible approach for most organs.
Have a heart problem. Just Hang in there for about 3 weeks while we print you one.
Stem cells do not have HLA markers. They are not recognized as self or non-self by the body, will not be rejected by the body once they are transformed to fully functioning hepatocytes. One problem that does exist, some of the transformed iPS cells may NOT transform. Once delivered to the patient these few untransformed cells could become pre-cancerous cells.
New way to grow healthy liver cells? I'll drink to that!
I believe and have believed for a long time that it will be our own skin cells which will emerge as superior to the 'pluripotent' stem cells long heralded as the answer. Murine skin cells from buccal mucosa HAVE ALREADY have already been used to clone living mice. A lot of this work went underground during the Bush era and is only now being published. A real leap ahead in treating malignant organs and systemic organ DZ is not far off. Your own dermatologist might be the go-to medical expert of the the near future when it comes to 'replacement' organs.
It is really interesting and a good step for those people who suffer with the liver diseases. It will helpful because this disease damaged the function of hapetocytes, it may causes hepatocellular necrosis, fibrosis, and regeneration with nodule formation. Turmeric, guduchi and milk thistles are the effective herb treatment. Apart of all this theory of the article is quite interesting.